منابع مشابه
Obesity and Kidney Disease
The rise in the prevalence of chronic kidney disease (CKD) and an increase in the prevalence of obesity in parallel in the recent years is a great concern. CKD increases the rate of cardiovascular disease (CVD) and development of end-stage renal disease, and leads to premature death. Although no direct causality link between obesity and CKD can yet be established, this appears highly probable. ...
متن کاملFerroptosis and cell death mechanisms in Parkinson's disease.
Symptoms of Parkinson's disease arise due to neuronal loss in multiple brain regions, especially dopaminergic neurons in the substantia nigra pars compacta. Current therapies aim to restore dopamine levels in the brain, but while these provide symptomatic benefit, they do not prevent ongoing neurodegeneration. Preventing neuronal death is a major strategy for disease-modifying therapies; howeve...
متن کاملEtiology and Outcome of Chronic Kidney Disease in Iranian Children
Background Considering the significant geographical and ethnical differences in pattern of incidence, etiology and outcome of chronic kidney disease (CKD), the present study aimed to assess the etiology and outcome of CKD in Iranian children. Materials and Methods In a cross-sectional study etiology and outcome of 372 children aged 3 months to 18 years with CKD was studied during the period 199...
متن کاملobesity and kidney disease
the rise in the prevalence of chronic kidney disease (ckd) and an increase in the prevalence of obesity in parallel in the recent years is a great concern. ckd increases the rate of cardiovascular disease (cvd) and development of end-stage renal disease, and leads to premature death. although no direct causality link between obesity and ckd can yet be established, this appears highly probable. ...
متن کاملFerroptosis: Death by Lipid Peroxidation.
Ferroptosis is a regulated form of cell death driven by loss of activity of the lipid repair enzyme glutathione peroxidase 4 (GPX4) and subsequent accumulation of lipid-based reactive oxygen species (ROS), particularly lipid hydroperoxides. This form of iron-dependent cell death is genetically, biochemically, and morphologically distinct from other cell death modalities, including apoptosis, un...
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ژورنال
عنوان ژورنال: Nefrología
سال: 2020
ISSN: 0211-6995
DOI: 10.1016/j.nefro.2020.03.005